Neuronal excitability provides indications of the biophysical properties of excitable membranes and of the dynamic aspects of ion channels in producing transient potentials. To study neuronal dynamics the experimental approach is based on the electrophysiology methods like patch-clamp tecniques. HOME

  • Santillo S., Changes in Biophysical Properties of Undifferentiated SH-SY5Y Cells During Long-Term Cultures, Neuroscience 2022, doi: 10.1016/j.neuroscience.2021.10.033
  • Santillo S. et al., Treating TB human neuroectodermal cell line with retinoic acid induces the appearance of neuron-like voltage-gated ionic currents, 2019, Brain Research 1711:97-105. doi: 10.1016/j.brainres.2019.01.019
  • Santillo S. et al., Membrane currents in Madin-Darby bovine kidney cells are enhanced by exposure to dioxin, 2019, BJSTR. https://biomedres.us/fulltexts/BJSTR.MS.ID.003252.php
  • Santillo S. et al., Electrophysiological variability in the SH-SY5Y cellular line, 2014, Gen. Physiol. Biophys. 33:121-129

The ETE-S compound, a small semiconducting organic molecule, induces modulation of the Hydra bioelectrical CPT pattern. HOME

  • G. Tommasini, et al., “In vivo neuromodulation of animal behavior with organic semiconducting oligomers”, Science Advances, 9 (2023), DOI:10.1126/sciadv.adi5488